Here are a couple of links to GIS software options for those working with Mac computers.
http://edcommunity.esri.com/software/mac/
http://www.uic.edu/cuppa/udv/GIS/ArcGISonMac200911.pdf
And here is a rather long list of other Mac GIS software options.
http://freegeographytools.com/2009/gis-related-software-for-the-mac

I’ve been using ArcGIS 9.3 on my Mac with Virtual Fusion. Pretty happy with it although definitely slower than on a PC. Has anyone moved to 10? If so, what has your experience been? Thanks!